Jon Brillman, M.D., F.R.C.P.I

Allegheny Neurological Associates,
Allegheny General Hospital, Pittsburgh PA.
 

Photo Credit: 
Horatio Alger Association
Career and Publications

Allegheny Neurological Associates
420 East North Avenue - Suite 206
Pittsburgh, PA 15212
(412) 321?2162

297 South Murtland Avenue
Pittsburgh, PA 15208
(412) 243-9663

EDUCATION

Graduate

1963-1967 University of Pittsburgh,  MEDICINE
 Pittsburgh, Pennsylvania

Undergraduate

1959-1963 University of Pennsylvania, English Literature, MAJOR HONORS
 Philadelphia, Pennsylvania 

 Post Graduate

1967-1968 Presbyterian University Hospital 
 Pittsburgh, Pennsylvania  - STRAIGHT MEDICINE

1968-1969 Presbyterian University Hospital 
 Pittsburgh, Pennsylvania - INTERNAL MEDICINE

1972-1975 Yale University  School of Medicine 
 New Haven, Connecticut RESIDENCY NEUROLOGY
1974 Institute of Neurology 
 Queens Square, London POST-GRADUATE FELLOW
 

EMPLOYMENT HISTORY

1975 - present ALLEGHENY GENERAL HOSPITAL 
 Pittsburgh, Pennsylvania SENIOR ATTENDING

1977 - present SEWICKLEY VALLEY HOSPITAL 
 Sewickley, Pennsylvania ASSOCIATE ATTENDING

1977 - present Ohio Valley Hospital 
 McKees Rocks, Pennsylvania CONSULTANT

1977-1999 Uniontown Hospital 
 Uniontown, Pennsylvania CONSULTANT

1995 - present St. Francis Medical Center 
 Pittsburgh, Pennsylvania CONSULTANT

1988-1994 Allegheny Neuropsychiatric Institute 
 Oakdale, Pennsylvania CONSULTANT

CERTIFICATION and LICENSURE

Commonwealth of Pennsylvania
1968,#010476E

Certified American Board of Psychiatry and Neurology
October 1976, #15736

National Board of Medical Examiners
1968,#93236

MILITARY SERVICE

1969-1971 U.S. Navy Submarine Service
 Lieutenant Commander
 USS George Bancroft SSBN643
 Medical and Diving Officer

HONORS AND AWARDS

Identified as one of Pittsburgh's "Top Doctors." Pittsburgh Magazine, 11/8 1.

Medical College of Pennsylvania, Golden Apple Award for excellence in teaching. Chosen by class of 1990?91.

Identified as one of Pittsburgh's "Top Doctors." Pittsburgh Magazine, 10/92.

Inducted Fellow of the Royal College of Physicians of Ireland, October 17, 1998, Dublin, Ireland

MEMBERSHIPS and OFFICES IN PROFESSIONAL SOCIETIES

American Academy of Neurology - Fellow
Pittsburgh Neuroscience Society
National Multiple Sclerosis Society - Advisory Board
American Society of Neuroimaging - Fellow
American Heart Association Stroke Council - Fellow
Association of University Professors in Neurology
American Medical Association
Pennsylvania Medical Society
Allegheny County Medical Society

PROFESSIONAL COMMITTEES and ADMINISTRATIVE SERVICE
 
Institutional
1976-1978 Critical Care Committee Allegheny General Hospital
1984-1985 Graduate Medical Education Committee Allegheny General Hospital
1985 - present  Executive Committee Medical Staff Allegheny General Hospital
1989-1992  Medical Ethics Committee Allegheny General Hospital, Chairman and Founder
1989 - present Admissions Committee Medical College of Pennsylvania
1991-1997  Council for Graduate Medical Education Allegheny General Hospital
1991- present  Medical Education Committee Medical College of Pennsylvania
1993 - present  Neuroscience's Research Center Advisory Committee Allegheny General Hospital
1993 - present  Duquesne and Medical College of Pennsylvania Task Force - Allegheny General Hospital
1993-1996  IHCS Committee  Allegheny General Hospital - Secretary
1994 - present  Medical College of Pennsylvania Allegheny Campus
 Executive Committee
1994-1998  Basic Neuroscience Curriculum  Allegheny Campus Co-Director
1995 - present  Advisory Committee for Professional Medical Development Medical College of Pennsylvania, Allegheny Campus
1996 - present  Member, Board of the Bayer School of Natural and Environmental Sciences, Duquesne University
1996 - present  Corporate Management Committee Allegheny General Hospital
1997 - present  Academic Department Chair Committee Allegheny General Hospital
1997 - present  Statewide Department Chairs and Center Directors Committee Allegheny General Hospital
1998   Partner Selection Committee Allegheny General Hospital
1998 - present  Search Committee for Chairman of Radiology - Allegheny University Allegheny General Hospital
2000 - present  Chairman, Search Committee for Chairman of Neurosurgery Allegheny General Hospital
Extramural
1976-1979  Epilepsy Foundation of America Board Member
1989 - present  Journal of Neuropsychiatry and Clinical Neuroscience Reviewer for Journal
October, 91 American Board of Psychiatry and Neurology Examiner, Part II, Philadelphia, PA
November, 92  American Board of Psychiatry and Neurology Examiner, Part II, New York, NY
1992 - Present  National Stroke Association Stroke Council Board Member
June, 93  American Board of Psychiatry and Neurology Examiner, Part II, Kansas City, KS
1993  Journal of Neuroimaging Reviewer
January, 94 American Board of Psychiatry and Neurology Examiner, Part II, Baltimore, MD
June, 94 American Board of Psychiatry and Neurology Examiner, Part II, Milwaukee, WS
1994  Editorial Board Journal of NeuroimagIng
November, 94 American Board of Psychiatry and Neurology Examiner, Part II, Boston, MA
May, 95 American Board of Psychiatry and Neurology Examiner, Part II, Washington, DC
July, 95  Subcommittee of ASN: Co-Chair - MRI - CT Examination Committee
July, 95  Search Committee for Chair of Neurology - MCP Hahnemann University
April, 96  American Board of Psychiatry and Neurology  Examiner, Part II, Philadelphia, PA
March, 97 American Society of Neuroimaging Board Member
1997  Present  Neurology Reviewer
February, 1998 Stroke Genetics Consortium Member
April, 1998  American Board of Psychiatry and Neurology Examiner, Part II, Chicago, IL
April, 1998   Western Pennsylvania Stroke Association Co-Chair
May, 1999  American Board of Psychiatry and Neurology
 Examiner, Part II, Boston, MA
March, 2000  Operation Stroke, Medical Sub-Committee Chairman

  EDUCATIONAL ACTIVITIES
 
1974-1975 Yale University School of Medicine Neurology 
 New Haven, Connecticut  - INSTRUCTOR
1988-1997 Medical College of Pennsylvania 
 Allegheny Campus Dept. of Neurology 
 Allegheny General Hospital 
 Pittsburgh, Pennsylvania - ACADEMIC CHAIRPERSON
1988-1997 Allegheny General Hospital  Pittsburgh, Pennsylvania Neurology  - DIVISION DIRECTOR
1988-1997 CLERKS IRP DIRECTOR
1988 - present Comprehensive Stroke Program - DIRECTOR
Allegheny General Hospital Pittsburgh, Pennsylvania
1988 - present  Medical College of Pennsylvania 
Allegheny Campus Dept. of Neurology
Allegheny General Hospital - PROFESSOR
1992-1997  Neurology Residency Program 
 Allegheny General Hospital
- PROGRAM DIRECTOR
1996 - present  John G. Rangos, Sr. School of Health 
 Sciences, Duquesne University
-CLINICAL PROFESSOR
1997 - present Allegheny General Hospital 
 Pittsburgh, Pennsylvania Dept. of Neurology
- CHAIRMAN

GRANT SUPPORT

The Central Neurological Effects of Coronary Artery Bypass Surgery: Transcranial Doppler Analysis of Cerebral Emboli during Coronary Bypass Graft Surgery and Neurologic Outcome as determined by Neuropsychiatric Evaluation.
Principle Investigator J. Brillman, M.D., Co-Investigator:  R.E. Clark, M.D.

Warner-Lambert Company, Food and Drug Administration (Protocol 970?58 A) "Treatment IND (Investigations New Drug) Protocol for the Use of Cognex (Tacrine Hydrocolloid) for the Management of Patients with Mild to Moderate Alzheimer's Dementia." Principal Investigator: Thomas F. Scott, M.D.
Co-Investigator:  J. Brillman, M.D.

"Computer-Aided Assessment of Adverse Effects of Antiepileptic Drugs."
Principal Investigator J. Valeriano, M.D.
Co-Investigator:  J. Brillman, M.D.

Safety and Efficacy of Depakote Monotherapy in the Treatment of Complex Partial Seizures: A Plasma Concentration - Response Study.
Abbott Laboratories.
Principal Investigator   J. Valeriano, M.D.
Co-Investigator: J. Brillman, M.D.

Low-dose Antiplatelet Therapy as Prophylaxis for Thromboemboli in Patients Receiving St. Jude Prosthetic Mitral Valves.
Grant - Syntex Corporation; $80,000/year for three years.
Principal Investigator :  J. Brillman, M.D.

A Multicenter, Double-blind, Placebo-controlled, Parallel Group Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Intravenous Selfotel in Patients with Acute Stroke. Grant - CIBA.
Principal Investigator:  J. Brillman, M.D.

Prospective Trial of Surgical vs. Non-Surgical Treatment in Patients Presenting Early after Spontaneous Supratentorial Intracranial Hemorrhage.
Principal Investigator J. Wilberger, M.D.
Co-Investigator:  J. Brillman, M.D.

A Randomized, Double-Blind, Placebo-Controlled Study of AVONEX (Interferon Beta-la) in the Treatment of Subjects at High Risk for Development of Multiple Sclerosis Following the First Onset of an Isolated Demyelinating Event. (Biogen Protocol Number C95-812)
Principal Investigator: T. Scott, M.D.
Co-Investigator:  J. Brillman, M.D.

High Intensity Transient Signals, Detected in the Middle Cerebral Artery During Cardiopulmonary Bypass Grafting: Correlation With Aortic Atheroma and Neuropsychologic Outcome. (Protocol Number RC- 1996)
Principal Investigator:  J. Brillman, M.D.
Co- Investigators: M. Malkowski, M.D., N. Reichek, M.D., J. Macgovern, M.D.,
 P. Snyder, Ph.D.

A Phase 2/3 Multicenter, Double Blind, Randomized, Placebo-Controlled Parallel Group Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Two doses of Intravenous Aptiganel Hydrochloride versus Placebo in Patients with Acute Ischemic Stroke (Protocol Number RC-2025)
Principal Investigator:  J. Brillman, M.D.

A Double-Blind, Parallel Group, Multinational, Multicenter study of the efficacy and safety of i.v. Clomethiazole compared to placebo in patients with acute ischernic stroke/with acute intracerebral hemorrhage/treated with t-PA (tissue plasminogen activator) for acute ischemic stroke. (Protocol 80545, SA-CMZ?0009/1 0/11)
Principal Investigator: J. Brillman, M.D.

An International, Multicenter, Double Blind, Randomized, Placebo-Controlled, Parallel Group Study to Access over three months the Safety, Efficacy, and Pharmaco-Econornics of an 800-mg loading dose and Five 200-mg maintenance doses of GV 150526 in the treatment of patients with a clinical diagnosis of Acute Stroke. (Protocol GLYA-3002)
Principal Investigator:  J. Brillman, M.D.

A Multinational, Multicenter, Double-blind, Placebo controlled study to evaluate the Efficacy, Tolerability and Safety of glatiramer acetate for injection in Primary Progressive Multiple Sclerosis patients. (Protocol 9008)
Principal Investigato T. Scott, M.D.
Co-Investigator:  J. Brillman, M.D.

A Multinational, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Tolerability and Safety of 2 Doses (5 mg and 50 mg) of Glatiramer Acetate Orally Administered in Relapsing Remitting Multiple Sclerosis Patients. (Protocol GA/7023)
Principal Investigator: T. Scott, M.D.
Co-Investigator: J. Brillman, M.D.

A Double-Blind Placebo Controlled Study of Effexor XR in Post Stroke Depression (Protocol #060OB 100526)
Principal Investigator Carol Schramke, Ph.D.
Co-Investigator:  Jon Brillman, M.D., Jacqueline Cavalier, C.R.N.P

GRADUATE STUDENTS

1993-1994 Raymond Girgis, M.D. Neurology Resident
1993-1996 David Lang, M.D. Neurology Resident
1994-1997 Paul Brill, M.D. Neurology Resident
1994-1997 Kumar Bhagavatula, M.D. Neurology Resident
1995-1996 Fani Manney, M.D. Neurology Resident
1995-1998 Jose DeOcampo, M.D. Neurology Resident
1995-1997 Rajnish Chaudhry, M.D. Neurology Resident
1996-1999 Michelle Wood, D.O. Neurology Resident
1996-1999 James Novero, M.D. Neurology Resident
1997-- present Berislav Spahija, M.D. Neurology Resident
1997-1998 Rafael Hurtado, M.D. Neurology Resident
1998 - present Mihaela Mihaescu, M.D. Neurology Resident
1998 - present Adriana Palade, M.D. Neurology Resident
1998-1999 Tuna Burgut, M.D. Neurology Resident
1999 - present Jiangping Liu, MD Neurology Resident
1999 - present Tatyana Barsouk, MD Neurology Resident

PUBLICATIONS

Peer & Non-Peer Reviewed:

 Peer Review

Brillman, J., Pincus JH: Myotonic Periodic Paralysis, Arch. Neurol. 29:67-69, 1973.

Brillman J., Howieson J: Transient Mid-Brain Syndromes as a Complication of Vertebral Angiography, J. Neurosurg. 41:71-74, 1974.

Brillman J: Acute Hydrocephalus and Death One Month Following Non-Surgical Treatment for Acute Cerebellar Hemorrhage, J. Neurosurg., Vol. 50 No. 3, March, 1978, pp. 374-376.

Brillman J: Migraine Prone Personality Concept Can Be Discarded, Clinical Psychiatry News, Vol. 7, 6, pp. 2, 1979.

Brillman J: Editorial "When We Die" Bulletin of the Allegheny County Medical Society, May 8, 1982.

Chatham PE, Brillman J: Transient Global Amnesia due to Bilateral Subdural Hematomas, Neurosurg. 971-973, December, 1985.

Brillman J, Adatepe M, Valeriano JP: The Diagnosis of Skull Base Metastases by Radionuclide Bone Scan, Cancer, 59:1887-91, 1987.

Valeriano JP, Brillman J: Recent Advances in Cerebrovascular Disease and the Value of a Stroke Referral Center and Unit, Neuroscience Journal, pp. 1, 1989.

Power T, Hanlon D, Brillman J: Dissections of the Cervicocerebral Arteries, Neuroscience Journal, pp. 9, 1989.

Brillman, J: Editorial Nihilism and Stroke, Neuroscience Journal, pp. 31, 1989.

Scott TF, Brillman J: Primary Central Nervous System. Lymphoma and AIDS, Neuroscience Journal, Vol 1, No. 3, pp. 20, 1990.

Scott TF, Hogan ED, Cater TD, Garen PD, Brillman J: Primary Intracranial Meningeal Lymphoma, The American Journal of Medicine, Vol. 89, pp. 536-538, October, 1990.

Scott TF, Goust JM, Strange C, Brillman J: Systemic Lupus Erythematosus, Thrombocytopenia, and HTLV- I Infection. Journal of Rheurnatology (Vol. 17 (11), pp. 1565-66, 1990).

Brillman J: Immunologic Mechanisms in the Paraneoplastic Syndromes. Neuroscience JournA Vol. 2 No. 2: pp. 26-8,1991.

Hanlon D, Power T, Brillman J: Spontaneous Dissections of the Cervicocerebral Arteries. Annals of Emergency Medicine: Vol. 20 (9); pp. 1032-35, September, 1991.

Brillman J, Rotheram E, Valeriano JP, Scott TF, Thomas L: The Magnetic Resonance Image Appearance of Mycoplasma Pneumonia Encephalopathy. Journal of Neuroimaging, January 1992, Vol. 2, No. 1, 42-44.

McConnell H, Valeriano J, Brillman J: "Trenuptial Seizures: A Report of Five Cases." Accepted for publication in J of Neuropsychiatry and Clin Neuroscience 1/5/93.

Scott TF, Price TR, George MS, Brillman J, Rothfus W: Midline Cerebral Malformation and Schizophrenia. Journal of Neuropsychiatry, Summer 1993, Vol. 5 No. 3: pp. 287-293.

Scott TF, Brillman J, Gross JA: Sarcoidosis of the Peripheral Nervous System. Neurol Res, December, 1993; 15:389-390.

Scott TF, Hess D, Brillman J: Antiphospholipid Antibody Syndrome Mimicking Multiple Sclerosis Clinically and by Magnetic Resonance Imaging. Arch Int. Med. 1994; 154:917-920.

Clark RE, Brillman J, Davis DA: Microemboli During CABG: Genesis and Effect on Outcome. The Journal of Thoracic and Cardiovascular Surgery, February 1995, Vol. 109 No. 2: pp.249-258.

Brillman J, Davis D, Clark RE, Lovell MR, Benckart DA: Increased MCA Flow Velocity During the Initial Phase of Cardiopulmonary Bypass May Cause Neurological Dysfunction. Journal of Neuroimaging, July 1995, Vol. 5 No. 3: pp.135-141.

Bailes JE, Brillman J, Nellis K, Molter G, Elrifai AM. The cardiac effects of intracranial hemorrhage. Surgical Neurolog . (Submitted 1995).

Elrifai AM, Bailes JE, Shih SR, Dianzumba S, Brillman J. Characterization of the cardiac effects of acute subarachnoid hemorrhage in dogs. , Stroke. April 1996, Vol. 27 No. 4: pp.737-742.

McConnell H, Snyder P, Duffy J, Weilburg J, Valeriano J, Brillman J, Cress K, Cavalier J: "Neuropsychiatric Side-Effects Related To Treatment With Felbamate". Journal Of Neuropsychiatry and Clinical Neurosciences, Summer 1996, Vol. 8: pp.341-346.

Brillman J, Kasdan R, Wechsler L: " The Neurologist As Neuroimager." (Views and Reviews) Neurology. February 1997, Vol. 48: pp. 303-306.

DeoCampo J, Brillman J, Levy D. "Stenting: A New Approach to Carotid Dissection". Journal of Neuroimaging, July 1997, Vol. 7: pp. 187-190.

Mihaescu M, Brillman J, Rothfus W. "Midbrain Ptosis due to Periaqueductal Infarct Following Cardiac Catheterization: Early Detection with Diffusion-Weighted Imaging". Journal of Neuroimaging, January 1999, Vol. 9: pp. 62-63. (Abstract)

Scott T, Brillman J. "Shunt Responsive Dementia in Sarcoid Meningitis: Possible Role for Cisternography". Journal of Neuroimaging, January 1999. Vol 9: pp. 61-62. (Abstract)

Mihaescu M, Brillman J, Rothfus W. "Midbrain Ptosis due to Periaqueductal Infarct Following Cardiac Catheterization: Early Detection with Diffusion-Weighted Imaging". Journal of Neuroimaging, (In Publication)

Brillman J: Dear Doctor Column through the Allegheny County Medical Society - Topic: New Treatment Options for Stroke. Pittsburgh Post?Gazette, Pittsburgh, Pennsylvania. February 16, 1999.

Magovern JA, Brillman J. "Minimally Invasive Surgical Closure of Patent Foramen Ovale". The Pennsylvania Association for Thoracic Surgery (Abstract - Submitted for Publication)

Palade A, Schramke C, Brillman J. "Association between Patent Foramen Ovale, Atrial Septal Aneurysm, and Stroke". Neurology, April 2000. Suppl 3: pp. 327. (Abstract)

BOOKS and BOOK CHAPTERS

Brillman J: "Transient Global Amnesia in Cases with Space Occupying Lesions" in Transient Global Amnesia and Related Disorders, Markowitsch BF (ed.) Hogrefe and Huber Publishers, Lewiston, NY pp. 48-57, 1990.

Brilhnan J: Guest Editor "Neurocardiology." Neurologic Clinics, April 1993, W.B. Saunders Company, Philadelphia, PA, May, 1993, Vol 11, No. 2.

Brillman J: The Neurological Complications of Coronary Artery Bypass Surgery "Neurocardiology," Neurologic Clinics, W.B. Saunders Company, Philadelphia, May, 1993, Vol 11, No. 2: pp. 475-495.

Brillman J, McConnell H: "Benign Intracranial Hypertensiorf 'in: Cerebrospinal Fluid in Neurology and Pvc ; H. McConnell and J. Bianchine (eds); Chapman & Hall/CNS Publisher, London, 1994, pp. 130-132.

Maroon JC, Kennerdell JS, Brillman J: Tumors of the Orbit. Neurosurgery Second Edition, Vol 1, Robert J. Willdris, M.D., Setti S. Rengachary, M.D. (eds); McGraw-Hill, Inc., 1996, Ch. 148, pp. 1481-1493.

Brillman J, Scott TF: Preoperative Evaluation, Risk Management, and Patient Selection in Microsurgical Carotid Endarterectomy, Lippincott-Raven Publishers, New York, NY, 1996, pp. 25-36.

Brillman J: The Neurological Complications of Cardiac Surgery in The Office Practice of Neurolog Martin A. Samuels, M.D. (ed.) Churchill Livingstone Inc., New York, NY, 1996, Part 8, Section 1: pp. 966?972.

Brillman J: "Neurological Evaluation in the Elderly," a volume in the Critical Issues in NeuropLPsychology, Antonio E. Puente, Ph.D. and Cecil R. Reynolds, Ph.D. (eds); Plenum Publishing Company, 1997, Ch. 23, pp. 351-359.

Brillman J: "Cardiothoracic Surgery" in Hospitalist Neurolog . Martin A. Samuels, M.D. (ed.) Butterworth?Heinemann, Newton, MA, 1999, Ch. 19, pp. 433-445.

Brillman J, Cowling K: "Gait Disturbances" in Emergency Neurology - Principles and Practice. Kevin Kelly, M.D., Ph.D. (ed.) Cambridge University Press, 1999, United Kingdom, Ch. 13, pp. 173-179.

Brillman J: "Transcranial Doppler Detection of Microemboli from the Heart" in Transcranial Doppler Ultrasono"a . Lawrence Wechsler, M.D. (ed.) Butterworth?Heinemann, Newton, MA, 1998, Ch. 12, pp. 175 - 178

LETTERS

Brillmm J, Cowling K: Emergency Management of Gait Disturbance in Shah S.M. and Kelly K.M. Emergency Neurology: Principles and Practice, Cambridge University Press (in press).

Brillman J: "Cardio-Thoracic Surgery." a volume in Hospital Consultation Neurolo ; Martin A. Samuels, M.D. (ed.) Butterworth-Heinemann (submitted for publication).

Brillman J: Complex Partial Seizures vs. Schizophrenia JAMA, July 18, 1977, Vol. 238, No. 3.

Scott TF, Brillman J: Cranial Neuropathy, Neurology: 41 January 1991, 157.

Scott TF, Brillman J, Romanelli J, Hess D: Anticardiolipin Antibodies in Multiple Sclerosis Patients (Letter to the Editor). ACTA Neurologica Scandinavica, 88:184-189, 1993.

McConnell H, Snyder P, Brillman J, Valeriano J, Cavalier J: Psychiatric Effects of Felbarnate (Letter to the Editor). Journal of Neuropsychiatry, Winter 1997, Vol. 9, pp. 118-119.

PRESENTATIONS (1989-Present)

Local and Regional

"Neurologic Update for General Physicians," Course Director, Allegheny General Hospital, Pittsburgh, PA, 1984.

"Stroke 1989 - Recent Advances and Future Hopes," Seminar ? Course Director, Allegheny General Hospital, Pittsburgh, PA, 1989.

"Recent Advances in Cerebrovascular Disease," Continuing Medical Education Program at Sewickley Valley Hospital, Sewickley, PA 11/5/89.

"Neurology of Aging;" 9th Annual Western Pennsylvania Conference of Aging, Seven Springs Resort, Champion, PA 10/27/89.

"Brain Death and Jewish Law;" Hebrew Institute of Pittsburgh, Pittsburgh, PA 1/22/92.

"Value of MRI," Western Pennsylvania Society of Nurses, Pittsburgh, PA 5/20/92.

"New Treatment of Options for Stroke Prevention," Medical Center of Beaver County, Grand Rounds, Rochester, PA 9/4/92.

"Physiology and Anatomy of Cerebral Circulation7 in course entitled "The Clinical Utility of Transcranial Doppler," Allegheny General Hospital, Pittsburgh, PA 10/17/92.

"New Strategies in Stroke Prevention," Frick Hospital Grand Rounds, Mt. Pleasant, PA 11/19/92.

"Treatment and Prevention of Stroke," The Hancock Medical Group, Wheeling, WV 1/12/93.

"Stroke Prevention Strategies in the 90's," Medical Grand Rounds, North Hills Passavant Hospital, Pittsburgh, PA 2/11/93.

"Cerebrovascular Disease," Medical Grand Rounds, Sacred Heart Hospital, Cumberland, MD 5/13/93.

McConnell H, Valeriano J, Cavalier J, Brillman J: "Psychiatric Aspects of Epilepsy" poster presented at the First Annual ANI Research Day, Allegheny Neuropsychiatric Institute, Oakdale, PA, December, 1993.

"New Concepts in Stroke Prevention," Medical Grand Rounds, Washington Hospital, Washington, PA 2/2/94.

"Antiplatelet Therapy in Stroke," Westmoreland County Medical Society, Greensburg, PA 3/15/94.

"Cerebral Blood Flow Changes in Cardiopulmonary Bypass," International Symposium in Advances in the Clinical Aspects of Cerebral Blood Flow, Allegheny General Hospital, Pittsburgh, PA 4/30/94.

International Symposium in Advances in the Clinical Aspects of Cerebral Blood Flow, Moderator, Afternoon Session; Allegheny General Hospital, Pittsburgh, PA 4/30/94.

"Antiplatelet Therapy in Stroke," Somerset Medical Group, Somerset, PA.

"Stroke Management in the Elderly: Post?Stroke Seizure Syndrome;" Fourteenth Annual Conference on Aging, Seven Springs Mountain Resort, Champion, PA 9/22/94.

"New Surgical Indications for Stroke," Allegheny County Medical Society, Southern Division 10/11/94.

"Management of Stroke Syndromes," Allegheny Neuroscience Institute Annual Cerebrovascular Symposium, Pittsburgh, PA 12/10/94.

"Interventional and Prophylactic Stroke Therapy," John F. Mulach Lecture, St. Clair Hospital, Upper St. Clair, PA 2/15/95.

"Thrombolytic Therapy for Stroke," Grand Rounds, Sewickley Valley Hospital, Sewickley, PA 2/28/95.

"Progress in Stroke Therapy," Grand Rounds, Citizens General Hospital, New Kensington, PA 5/23/95.

"Therapy of Parkinson's Disease," Parkinson's Disease Foundation Local Chapter, Sheraton Hotel Station Square, Pittsburgh, PA9n195.

"Preventive and Interventional Therapy for Stroke," New Therapies for Neurological Disorders, Allegheny General Hospital, Pittsburgh, PA 9/15/95.

"Neurological Evaluation of Stroke Syndromes and Results of Recent Clinical Trials," Carotid Endarterectomy Workshop, Duquesne University, Pittsburgh, PA 9/16/95.

"Therapy for Stroke," Stroke Prevention Lecture Program, Top of the Triangle Restaurant, Pittsburgh, PA 10/26/95.

"Neuropsychiatric Complications of Open-Heart Surgery," Grand Rounds, St. Francis Hospital, Pittsburgh, PA 12/7/95.

"Classification and Current Medical Management of Stroke," Allegheny Neuroscience Institute Second Annual Cerebrovascular Symposium, Pittsburgh, PA 12/9/95.

"Preventative and Interventional Stroke Therapy: An Update," Grand Rounds, McKeesport Hospital, Pittsburgh, PA 2/6/96.

"Assessment and Management of Patients With Symptomatic and Asymptomatic Carotid Stenosis," Sixth Annual New Dimensions in Cardiology for the Primary Care Physician, Pittsburgh, PA 3/9/96.

"Ticlid and Therapeutic Options in Stroke," Roche Laboratories Lecture, Top of the Triangle Restaurant, Pittsburgh, PA 5/22/96

"Neurological Effects of Open Heart Surgery," Grand Rounds, Allegheny University of the Health Sciences, MCP * Hahnemann School of Medicine, Center City Campus, Philadelphia, PA 10/4/96.

"Brain Attack," Emergency Symposium, Allegheny General Hospital, Pittsburgh, PA 11/08/96

"Update on Stroke," Roche Laboratories Lecture for the Washington Medical Society, Top of the Triangle Restaurant, Pittsburgh, PA 03/19/97

"Current Treatment for Stroke," DuPont Pharmaceutical Lecture, Latrobe Area Hospital, Latrobe, PA 01/24/98

"New Preventive and Interventional Treatment of Stroke", Allegheny General Hospital, Pittsburgh, PA 04/03/98

"Management of Hypertension in Acute Stroke", "Role of Heparin in Acute Stroke", "Neuroprotective Agents", American Academy of Neurology Workshop on Acute Stroke Management, Marriott, Pittsburgh, PA 05/16/98

"Interventional Stroke Management" East Suburban Hospital ? West Penn - Forbes Regional Campus Grand Rounds, Monroeville, PA, 01/13/99

"Stroke Prevention Strategies for the 90's" DuPont Pharmaceutical Lecture, UPMC Lee Hospital, Johnstown, PA 01/21/99

"Stroke Prevention in the Elderly" Boehringer Ingelheim Pharmaceuticals Lecture, Seven Springs Mountain Resort, Champion, PA 09/17/99

"New Approaches to Stroke Management and Prevention7 Boehringer Ingelheim Pharmaceuticals Lecture, Rizzo's Restaurant, Windber, PA 10/07/99

"New Approaches to Stroke Management and Prevention" Boehringer Ingelheim Pharmaceuticals Lecture, Penn Brewery, Pittsburgh, PA 11/18/99

"New Approaches in Stroke Preventiorf ' Boehringer Ingelheim Pharmaceuticals Lecture, Carlton Restaurant, Pittsburgh, PA 03/16/00

"Operation Stroke Sub-Committees" at the Operation Stroke Task Force Briefing, Allegheny County Courthouse, Gold Room, Pittsburgh, PA 04/06/00

National

"The Central Nervous System Effects of Coronary Artery Bypass Surgery," Neurocardiology Course -

MA Samuels, Director. American Academy of Neurology Courses. AAN Annual Meeting, San Diego, CA 5/3/92.

"Strategies in the Treatment and Prevention of Stroke," Neurology Grand Rounds, University of Kansas, Kansas City, KS 5/7/93.

Professor Rounds, University of Kansas, Kansas City, KS 5/7/93.

"Cerebrovascular Disease Discussing Recent Advances in Stroke Prevention," Faculty Sponsored by Syntex Laboratories, Bolton Landing, NY 8/2-3/93.

"Aspirin Treatment versus Tichd Treatment for Stroke," Third Annual Neuroscience Conference for Primary Care Physicians, Peak'n Peak, Erie, PA 9/11/93.

Professor Rounds, Conemaugh Valley Memorial Hospital, Johnstown, PA 11/3/93.

"Indications for Surgical Intervention in Cerebrovascular Disease," Grand Rounds, Conemaugh Valley Memorial Hospital, Johnstown, PA 11/3/94.

"Microemboli During CABG. Genesis and Effect on Outcome," 74th Annual Meeting of the American Association for Thoracic Surgery, New York City, NY 4/25/94. Authors: Brillman J, Clark RE, Davis DA, Lovell M, and Magovern G.

"The Source of Microemboli During CABG Surgery and the Neurological and Cognitive Sequelae," Brain and Cardiac Surgery Conference, Key West, FL 9/24/94.

PRESENTATIONS

"The Neurological Complications of Cardiopulmonary Bypass Surgery," Grand Rounds: Medical City Hospital, Dallas, TX 10/7/94.

Prophylactic and Interventional Stroke Therapy," Crozer Chester Medical Center, Philadelphia, PA 12/12/95.

"TCD and Cardiopulmonary Bypass," Cerebral Hemodynamics and Embolism 1996, Dallas, TX 1/22/96.

"Ticlopidine in the Prevention of Stroke" Antithrombotic Therapy in Clinical Practice, University Hospitals of Cleveland, Cleveland, OH 04/08/98.

"Stroke Associated with Heart Surgery", Distinguished Alumnus Lecture, Grand Rounds: Yale University School of Medicine, New Haven, CT 06/23/98.

Mihaescu M, Brillman J, Rothfus W. "Midbrain Ptosis due to Periaqueductal Infarct Following Cardiac Catheterization: Early Detection with Diffusion Weighted Images" Presented at the 22d Annual Meeting of the American Society of Neuroirnaging: Scottsdale, Arizona, February 24-27, 1999, J Neuroirnaging, January 1999:9 (Abstract Presentation), pp. 62?63.

Scott T, Brillman J: "Shunt Responsive Dementia in Sarcoid Meningitis: Possible Role for Cisternography. Presented at the 22d Annual Meeting of the American Society of Neuroirnaging: Scottsdale, Arizona, February 24-27, 1999, J Neuroirnaging, January 1999:9 (Abstract Presentation), pp. 61.

International

Brillman J, Davis DA, Clark RE, Lovell. MR: Transcranial Doppler Evaluation of Flow Velocities in the Middle Cerebral Artery During the Initial Phase of Cardiopulmonary Bypass, Fifth Meeting of the Neurosonology Research Group, World Federation of Neurology, Toronto, Canada 9/3/93.

Brillman J, Davis DA, Clark RE: Transcranial Doppler Evaluation of Flow Velocity in the Middle Cerebral Artery During the Initial Phase of Cardiopulmonary Bypass. Third Intnl. Conference on Heart-Brain Interactions; Bologna, Italy 10/25-26/93. Poster.

Brillman J, "Stroke as a Cause of Epilepsy" Lecture at Maudsley Hospital, London, U.K. 4/10/97.

Bfilhnan J, "Stroke Management in the year 2000", "Neurological Complications of Open Heart Surgery" Two lectures and nine days of service. Dar Al Fouad Hospital, Cairo, Egypt 12/1/99 to 12/10/99.


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