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Each year, the lives of thousands of people across the country are saved because someone made the choice to become an organ donor. In April, Allegheny Health Network is honored to celebrate National Donate Life Month and pay tribute to all of those who have bestowed the precious gift of life to another through organ donation. Visit AHNdonate.org to learn more and register to be an organ donor.



Format: 04/25/2014
Format: 04/25/2014


Allegheny Singer Research Institute Scientists Awarded NIH Grants as Part of National Recovery Act Fund

Monday, October 19th, 2009

Six innovative research projects being led by physicians and scientists from Allegheny Singer Research Institute (ASRI), the research arm of Allegheny General Hospital (AGH), have been selected to receive grant awards under the American Recovery and Reinvestment Act of 2009 (Recovery Act). 

Established as part of the Obama administration’s efforts to stimulate the national economy, the Recovery Act will infuse $5 billion into the National Institute’s of Health (NIH) budget to fund more than 12,000 grants for cutting-edge medical research projects across the country. It is the largest single capital investment in biomedical research in the nation’s history and is expected to support tens of thousands of jobs over the next two years in the biomedical industry.

The NIH’s grant awards will support a full spectrum of basic, clinical and translational research endeavors in such critical areas as cardiovascular disease, autism, HIV-AIDS, H1N1 influenza and cancer.

At ASRI, approximately $2 million in NIH Recovery Act grants have been awarded to researchers exploring breakthroughs in ischemic stroke, infectious disease and gene therapy for lysosomal storage diseases. Among the projects being funded include;

Impact of Antibiotics and Vaccines on the In Vivo Evolution of S. Pneumoniae and the Molecular Analysis of Pathogens in Otitis Media by PCR - principal investigator Garth Ehrlich, Ph.D., executive director of the ASRI/AGH Center for Genomic Sciences.

Brain K+ Dynamics, BBB Breakdown & Hemorrhagic Transformation in Ischemic Stroke and Ischemic Edge Dynamics In Ischemic Stroke: Potassium and the Blood-Brain Barrier - principal investigator Stephen Jones, Ph.D., AGH Neurosciences Research Institute.

Salivary Gland-Based Gene Therapy for Lysosomal Storage Diseases - principal investigator Michael Passineau, Ph.D., AGH Center for Cardiovascular Disease Research.

“We are extremely proud and gratified to have the significant work of our researchers further validated through the Recovery Act initiative. This funding will expedite the progress on these important projects and bring the promise each offers for improving the management of disease closer to the bedside,” said Christopher Post, MD, Ph.D., ASRI president and scientific director.

About ASRI:
Allegheny-Singer Research Institute (ASRI) is a non-profit, independent research institute and a member of the West Penn Allegheny Health System (WPAHS). As the research component of Allegheny General Hospital (AGH), ASRI’s vision is to facilitate the advancement of translational and clinical research in harmony with the clinical strengths of Allegheny General Hospital for improved patient care. Our mission is to sponsor superior collaborative interdisciplinary programs in health, education , and research in order to promote the understanding, treatment and prevention of human disease. The Institute has a synergistic and professional research culture throughout its organization from its customer support driven administrative team to its innovative physicians and scientists. Together, the common goal is to develop and disseminate new methods and technologies for advanced care in the areas of cardiovascular/pulmonary, oncology , human genetics, neuroscience and musculoskeletal medicine.



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