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Format: 04/18/2014
Format: 04/18/2014

News

Reuters: Binghamton research group develops new cancer treatment

Thursday, September 17th, 2009

BINGHAMTON, N.Y., Sept. 16 /PRNewswire/ -- After years of innovation and
intensive research, a team of Binghamton University (BU) researchers working
with Cell Preservation Services, Inc., Owego, NY has broken extraordinary new
ground in the recognition of cryosurgery as a primary treatment option for
prostate cancer. The American Urological Association recently issued a Best
Practices Statement that recommends cryosurgery of the prostate as both a
primary and salvage therapy for patients with prostate cancer.

It was the team's discovery of a previously unrecognized form of cell death
"apoptosis" and its research into the varying effects of treatment on
different types of prostate cancer that led to the advanced technology that
now makes cryosurgery of the prostate possible. The team working in
partnership with physicians at Pittsburgh's Allegheny General Hospital has
revolutionized the way prostate cancer is treated and continues to lead
research into the advancement of treatment.

The recommended use of cryosurgery as a primary treatment comes as BU team
leader Dr. John G. Baust, also a Professor of Biological Sciences at BU and
UNESCO Chair, received a rare honor for his world-wide leadership in
cryomedicine and his work with the BU team. The international Society for
Cryobiology, recently elected Baust to the prestigious position of Fellow of
the Society. He is one of only ten to receive this recognition from the
Society.

As team leader, Baust directed fellow researchers in their quest to develop
the surgical devices necessary to precisely apply the freezing temperatures to
the prostate and work out the "biology of the disease" and its responses to
freezing. The Allegheny General team developed the surgical protocols and
managed the patients during the years that followed treatment to assure a
successful outcome. Both teams partnered to teach this new therapy to many
thousands of urologic surgeons and interventional radiologists at many of the
major medical universities in the U.S. and Europe.

The key to perfecting the treatment came through an in-depth study that delved
into to the molecular biology of prostate cancer and low temperature responses
conducted by Dr. Robert Van Buskirk, Professor of Biological Sciences &
Bioengineering. That's when Dr. William Hollister, a former BU graduate
student now on the faculty of BCC, made a critical discovery, identifying a
previously unrecognized form of cell death following freezing known as
"apoptosis" in a population of dying cancer cells.

To read more, visit the Reuters web site.

 

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