Chronic Fatigue Syndrome

Chronic fatigue syndrome is associated with both sleeping disorders and activated immune systems. Some researchers believe this condition may be set off by an infection that activates the immune system, and then the immune system doesn't shut down. But the cause is not known, nor is the cure.

Diagnosis
There is no diagnostic test for chronic fatigue syndrome. In addition, its symptoms could stem from a number of other medical conditions. Therefore, the physician must first rule out any other illnesses by conducting a detailed medical history, blood tests and other diagnostic procedures.

Treatments
Once all other medical conditions that could cause these symptoms are ruled out, the diagnosis of chronic fatigue syndrome can be made. The symptoms can then be treated with one, or a combination of, the following types of medications:

• Serotonin blockers such as Prozac® Zoloft® or Paxil®. By blocking serotonin, a chemical in the brain, these medications act as stimulants and may improve the patient's mood.
• Nonsteroidal anti-inflammatory medications like ibuprofen to relieve body aches and joint pain.
• Tricyclic antidepressants (doxepin, amitriptyline, imipramine). These medications promote sleep and alter the brain's ability to perceive pain.

Some of these medications take four to six weeks to become effective. And, patients are likely to be taking them for months, or even years, because the symptoms of chronic fatigue syndrome can last that long.

Mild to moderate exercise also is prescribed to help patients regain some of their strength and endurance. This part of the treatment regimen is often the most difficult for patients whose fatigue and aches have made them sedentary.

The illness causes a vicious cycle: The less activity you have, the weaker your body becomes, and the weaker you feel, the less you do. Many patients end up on a downward spiral that could get to the point where they can't even get out of bed."

Last Updated: December 03, 2007