Cystic Fibrosis

Cystic Fibrosis is an inherited disease that affects the respiratory and digestive systems. It affects the mucus and sweat glands of the body and is caused by a defective gene. Thick mucus is formed in the breathing passages in the lungs and this predisposes the person to chronic lung infections. Many pancreatic enzymes involved in the breakdown and absorption of fats in the intestine are absent, causing malabsorption (inadequate absorption of nutrients from the intestinal tract) and malnutrition.

Screening of family members of a cystic fibrosis patient may detect the cystic fibrosis gene in between 60 and 90% of carriers, depending on the test used.

Symptoms
Symptoms of cystic fibrosis include:

• No meconium (bowel movements) in first 24-48 hours of life
• Stools, pale or clay colored, foul smelling or stools that float
• Skin may taste salty (infants)
• Recurrent persistent respiratory infections such as pneumonia or sinusitis
• Coughing or wheezing
• Weight loss
• Diarrhea
• Delayed growth
• Easy fatigue

Treatment
Early recognition of cystic fibrosis and a comprehensive, multidisciplinary treatment program can lengthen survival time and improve the quality of life.

Last Updated: December 03, 2007