Research

Thoracic Cancer Clinical Trials

The following clinical trials related to thoracic cancers are available through the WPAHS. Please click on the link for more detailed information on the trial. Below each trial is the contact information at the WPAHS.

Esophageal Cancer

Study Title

A Phase II Study of Neoadjuvant Therapy with Cisplatin, Docetaxel, Panitumumab plus Radiation Therapy followed by Surgery with Locally Advanced Adenocarcinoma of the Distal Esophagus

Principal Investigator: Robert Keenan, M.D.

Please also contact study coordinator for more information:

Irina Barskaya, MD, CRA (412.359.6165)

Internal Reference: (RC- 4759/Z4051 Keenan)

Study Title

RTOG 0436: A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients with Esophageal Cancer who are Treated without Surgery

Principal Investigator: David Parda, M.D.

Please also contact study coordinator for more information:

Judy Negley, CCRP (Phone 412.359.4046)

Internal Reference: (RC4831/RTOG Parda)

Non-Small Cell Lung Cancer

Study Title

S0819, A Randomized Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)

Principal Investigator: Dulabh Monga, M.D.

Please also contact study coordinator for more information:

Gloria Flannery, RN (Phone 412.359.8379)

Internal Reference: (RC-4993/CTSU SWOG Monga)

Study Title

A Randomized Phase III Trial of Adjuvant Therapy in Early Stage Non-small Cell Lung Cancer Evaluating the Potential Utility of a Genomic Prognostic Model to Identify Patients as Candidates for Adjuvant Chemotherapy

Principal Investigator: Robert Keenan, M.D.

Please also contact study coordinator for more information:

Irina Barskaya, MD, CRA (412.359.6165)

Internal Reference: (RC-4793 /CALGB 30506 Keenan)

Study Title

A Phase III Randomized Trial of Lobectomy Versus Sublobar Resection for Small (≤ 2 CM) Peripheral Non-Small Cell Lung Cancer

Principal Investigator: Robert Keenan, M.D.

Please also contact study coordinator for more information:

Irina Barskaya, MD, CRA (412.359.6165)

Internal Reference: (RC-4394/CALGB 140503 Keenan)

Study Title

The Cancer and Leukemia Group B (CALGB) Lung Cancer Tissue Bank

Principal Investigator: Robert Keenan, M.D.

Please also contact study coordinator for more information:

Irina Barskaya, MD,CRA (412.359.6165)

Internal Reference: (RC- 4407/CALGB 140202 Keenan)

Study Title

A Randomized Double-blind Multicenter Phase III Trial for Advanced or Recurrent Non Small Cell Lung Cancer Patients After Failure of First Line Therapy

Principal Investigator: Mohammed Islam, M.D.

Please also contact study coordinator for more information:

Rich Wonder, RN, CCRC (Phone 412.578.4492)

Internal Reference: (IRB10-033/Islam)

Study Title

RTOG 0617: A Randomized Phase III Comparison of Standard-Dose (60 Gy) Versus High Dose (74 Gy) Conformal Radiotherapy with Concurrent and Consolidation Carboplatin/Paclitaxel +/- Cetuximab (IND #103444) in Patients with Stage IIIA/IIIB Non-Small Cell Lung Cancer

Principal Investigator: David Parda, M.D.

Please also contact study coordinator for more information:

Judy Negley, CCRP (Phone 412.359.4046)

Internal Reference: (RC4499/RTOG Parda)

Study Title

A Double-Blind , Randomized, Placebo-Controlled
Phase III Study of Adjuvant Therapy in Patients with Resectable
Non-Small Cell Lung Cancer

Principal Investigator: Robet Keenan, M.D.

Please also contact study coordinator for more information:

Irina Barskaya, MD, CRA (412.359.6165)

Internal Reference: (RC-5012/ Keenan)

Study Title

A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy)Versus Stereotactic Body Radiation Therapy in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)

Principal Investigator: Rober Keenan, M.D.

Please also contact study coordinator for more information:

Irina Barskaya, MD, CRA (412.359.6165)

Internal Reference: (RC-5268/ACOSOG Z4099 Keenan)